Infection of human oligodendroglioma cells by a recombinant measles virus expressing enhanced green uorescent protein
نویسندگان
چکیده
1Neuropathology Laboratory, Royal Group of Hospitals Trust, Belfast, Northern Ireland, United Kingdom; 2School of Biology and Biochemistry, The Queen’s University of Belfast, Belfast, Northern Ireland, United Kingdom; 3School of Medicine, The Queen’s University of Belfast, Belfast, Northern Ireland, United Kingdom; 4Department of Biology, University of Oldenberg, Oldenberg, Germany; and 5INRS-Institut Armand-Frappier, 531 Boulevard des Prairies, Laval, Quebec, Canada
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In vitro and in vivo infection of neural cells by a recombinant measles virus expressing enhanced green fluorescent protein.
This study focused on the in vitro infection of mouse and human neuroblastoma cells and the in vivo infection of the murine central nervous system with a recombinant measles virus. An undifferentiated mouse neuroblastoma cell line (TMN) was infected with the vaccine strain of measles virus (MVeGFP), which expresses enhanced green fluorescent protein (EGFP). MVeGFP infected the cells, and cell-t...
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